The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Effect of BODUOPAESAN(BOS) on Gastrointestinal Tract

오패산(烏貝散)과 보두(寶豆)의 병용투여(倂用投與)가 위장관(胃腸管)에 미치는 영향(影響)

  • Kim, Tae-Woon (Dept. of Oriental Medicine Graduate School of Tae Jon University) ;
  • Cho, Chong-Kwan (Dept. of Oriental Medicine Graduate School of Tae Jon University)
  • 김태운 (대전대학교 한의과대학 내과학교실) ;
  • 조종관 (대전대학교 한의과대학 내과학교실)
  • Published : 1994.08.31
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Abstract

In order to investigate the effect of BODUOPAE-SAN(BOS), experiments were performed on analgesic effect induced by acetic acid, duration of hypnosis induced by pentobarbital-Na in mice and gastric ucler in Shay rats and indomethacin induced gastric ulcer, HCI-ethanol induced gastrci lesion in rats and gastric juice secretion in Shay rats. The results are as followings. 1. BOS showed significantly an analgesic effect induced by acetic acid. 2. BOS prolonged the duration of hypnosis induced by pentobarbital-Na in rats 3. BOS rised the spontaneous motility of isolatied ileum of mice temporarily. 4. BOS depressed the gastric motility of rats significantly. 5. BOS showed an anti-ulcer effect in Shay rats and indometacine-induced ulcer rats significantly. 6. BOS reduced the ulcer index of the HCl-ethanol induced gastric lesion in rats. 7. BOS reduced the gastric juice secretion in Shay rats. From above results think BOS is more effective in comparison to the OPAESAN alone on gastrointestinal disorder.

Keywords

References

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