Journal of Pharmaceutical Investigation

The Korean Society of Pharmaceutical Sciences and Technology (한국약제학회)
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Determination of Selenium in Dried Yeast Preparations

셀레늄 함유 건조효모제제 중 셀레늄 분석방법에 관한 연구

  • Oh, Sea-Jong (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Oh, Young-Taek (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Yoon, Won-Yong (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Park, Sung-Bae (Seoul Metropolitan Government Institute of Health and Environment)
  • 오세종 (서울특별시보건환경연구원) ;
  • 오영택 (서울특별시보건환경연구원) ;
  • 윤원용 (서울특별시보건환경연구원) ;
  • 박성배 (서울특별시보건환경연구원)
  • Published : 1994.03.20
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Abstract

In order to improve the sensitivity of the current assay methods of selenium in dried-yeast preparations, atomic absorption spectrophotometry (AAS), high performance liquid chromatography (HPLC) and UV-Vis spectrophotometry were employed. The sample was prepared with the digestion by acid mixture of hydrochloric acid, nitric acid and perchloric acid after elimination of ether-soluble substances. The range of quantitation of selenium was $1.0{\sim}6.0\;{\mu}g/ml$ by UV-Vis spectrophotometry, $5.0{\sim}20.0\;{\mu}g/ml$ by HPLC and $0.03{\sim}0.10\;{\mu}g/ml$ by AAS.

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