Journal of Pharmaceutical Investigation

  • 제24권1호
  • /
  • Pages.25-28
  • /
  • 1994
  • /
  • 2093-5552(pISSN)
  • /
  • 2093-6214(eISSN)
한국약제학회 (The Korean Society of Pharmaceutical Sciences and Technology)
권호 표지

연질캅셀제중 수용성 비타민의 젤라틴층 이행에 관한 연구

Migration of Water-Soluble Vitamins into Gelatin Layer of Soft Capsules

  • 오세종 (서울특별시보건환경연구원) ;
  • 박원희 (서울특별시보건환경연구원) ;
  • 윤광재 (서울특별시보건환경연구원) ;
  • 윤원용 (서울특별시보건환경연구원)
  • Oh, Sea-Jong (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Park, Won-Hee (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Yun, Kwang-Jai (Seoul Metropolitan Government Institute of Health and Environment) ;
  • Yoon, Won-Yong (Seoul Metropolitan Government Institute of Health and Environment)
  • 발행 : 1994.03.20
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초록

The previous vitamin assays in soft capsules have been performed only with capsule contents. Since some vitamins, however, could migrate into gelatin layer of the soft capsules, each vitamin of multivitamin soft capsules in the market was analyzed simultaneously in both capsule content and gelatin layer. The results showed that migrations of nicotinamide and pyridoxine hydrochloride into gelatin layer were pronounced, while those of other vitamins were negligible.

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