Antineoplastic Effect of Extracts from Traditional Medicinal Plants and Various Plants (II)

전통 약용식물 및 각종 식물의 항암효과에 대한 연구(II)

  • Hyun, Jin-Won (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Lim, Kyoung-Hwa (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Shin, Jin-E (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Sung, Min-Sook (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Oh, Jae-Hwan (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Yang, Yong-Man (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Won, Yong-Jin (Natural Products Research Institute, Seoul National University) ;
  • Kim, Yeong-Shik (Natural Products Research Institute, Seoul National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University) ;
  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
  • Paik, Woo-Hyun (Central Research Institute, Boryung Pharmaceutical Co., Ltd.) ;
  • Kim, Hyoung-Ja (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Woo, Eun-Rhan (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Park, Ho-Koon (Division of Applied Science, Korea Institute of Science and Technology) ;
  • Park, Jae-Gahb (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine)
  • 현진원 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 임경화 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 신진이 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 성민숙 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 오재환 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 양용만 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 원용진 (서울대학교 천연물과학연구소) ;
  • 김영식 (서울대학교 천연물과학연구소) ;
  • 강삼식 (서울대학교 천연물과학연구소) ;
  • 장일무 (서울대학교 천연물과학연구소) ;
  • 백우현 (보령제약 주식회사 중앙연구소) ;
  • 김형자 (한국과학기술연구원) ;
  • 우은란 (한국과학기술연구원) ;
  • 박호군 (한국과학기술연구원) ;
  • 박재갑 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부)
  • Published : 1994.12.31

Abstract

Antineoplastic activity against human gastric and colon carcinoma cell lines was measured in 49 extracts from 46 plants using MTT (3-[4, 5-dimethyl thiazol-2-yl]-2, 5-diphenyl tetrazolium bromide) method. Six extracts from five plants have been reported to have antineoplastic effect. Extracts from remaining 41 plants failed to show significant cytotoxic effect at the concentration of less than $230\;{\mu}g/ml$.

Keywords