Korean Journal of Pharmacognosy (생약학회지)
- Volume 25 Issue 4 Serial No. 99
- /
- Pages.363-367
- /
- 1994
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
Development of Plant Anti-inflammatory Agents : Comparison of Anti-inflammatory and Analgesic Activities of Extracts from Lonicera japonica
식물성 항염증제의 개발 : 인동추출물에 대한 항염증 및 진통작용의 비교
- Lee, Song-Jin (College of Pharmacy, Kangweon Nat'l Univ.) ;
-
Son, Kun-Ho
(Dept. Food Nutrition, Andong Nat'l Univ.)
;
- Chang, Hyeun-Wook (College of Pharmacy, Yeungnam Univ.) ;
-
Kang, Sam-Sik
(Natural Products Research Institute, Seoul Nat'l Univ.)
;
- Park, Pyeong-Uk (R & D Center, Sunkyong Industries) ;
- Kawk, Wie-Jong (R & D Center, Sunkyong Industries) ;
- Han, Chang-Kyun (R & D Center, Sunkyong Industries) ;
- Kim, Hyun-Pyo (College of Pharmacy, Kangweon Nat'l Univ.)
- 이송진 (강원대학교 약학대학) ;
-
손건호
(안동대학교 식품영양학과)
;
- 장현욱 (영남대학교 약학대학) ;
-
강삼식
(서울대학교 천연물과학연구소)
;
- 박병욱 (선경인더스트리 연구소) ;
- 곽의종 (선경인더스트리 연구소) ;
- 한창균 (선경인더스트리 연구소) ;
- 김현표 (강원대학교 약학대학)
- Published : 1994.12.31
Abstract
For developing plant anti-inflammatory agents, extracts from Lonicera japonica were obtained and evaluated for their anti-inflammatory and analgesic activities using acute/chronic inflammatory models and writhing tests. It was found that the extracts with a modified extraction method showed higher anti-inflammatory and analgesic activities than those of the extracts based on the ancient literatures.
Keywords
- Lonicera japonica;
- anti-inflammatory activity;
- analgesic effect;
- acute inflammation;
- chronic inflammation;
- mice ear edema test;
- adjuvant-induced arthritis test;
- acetic acid-induced writhing test