생약학회지 (Korean Journal of Pharmacognosy)
- 제25권4호통권99호
- /
- Pages.319-327
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- 1994
- /
- 0253-3073(pISSN)
- /
- 2288-9299(eISSN)
배초향 지하부의 Diterpene 성분과 그 세포독성
Diterpenoids from the Roots of Agastache rugosa and their Cytotoxic Activities
- 이형규 (한국과학기술연구원 유전공학연구소) ;
- 변순정 (중서약국) ;
-
오세량
(한국과학기술연구원 유전공학연구소)
;
- 김정일 (한국과학기술연구원 유전공학연구소) ;
-
김영호
(한국과학기술연구원 유전공학연구소)
;
-
이정옥
(한국화학연구소)
- Lee, Hyeong-Kyu (Genetic Engineering Research Institute, KIST) ;
- Byon, Soon-Jung (Joong-Seo Pharmacy) ;
-
Oh, Se-Ryang
(Genetic Engineering Research Institute, KIST)
;
- Kim, Jung-Il (Genetic Engineering Research Institute, KIST) ;
-
Kim, Young-Ho
(Genetic Engineering Research Institute, KIST)
;
-
Lee, Chong-Ock
(Korean Research Institute of Chemical Technology)
- 발행 : 1994.12.31
초록
A new diterpene, agastanol[1] with dehydroagastol[2] was isolated from th root of Agastache rugosa, and their structures were elucidated by chemical and instrumental analysis. Agastanol[1], its derivatives, agastanone[3] and methylagastanol[5], and dehydroagastol[2] showed cytotoxic activites against in vitro human cancer cell lines. Agastanol[1] showed weak antifungal activity against Trichophyton rubrum.
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