Diterpenoids from the Roots of Agastache rugosa and their Cytotoxic Activities

배초향 지하부의 Diterpene 성분과 그 세포독성

  • 이형규 (한국과학기술연구원 유전공학연구소) ;
  • 변순정 (중서약국) ;
  • 오세량 (한국과학기술연구원 유전공학연구소) ;
  • 김정일 (한국과학기술연구원 유전공학연구소) ;
  • 김영호 (한국과학기술연구원 유전공학연구소) ;
  • 이정옥 (한국화학연구소)
  • Published : 1994.12.31

Abstract

A new diterpene, agastanol[1] with dehydroagastol[2] was isolated from th root of Agastache rugosa, and their structures were elucidated by chemical and instrumental analysis. Agastanol[1], its derivatives, agastanone[3] and methylagastanol[5], and dehydroagastol[2] showed cytotoxic activites against in vitro human cancer cell lines. Agastanol[1] showed weak antifungal activity against Trichophyton rubrum.

Keywords