수종의 생약으로부터 혈소판 활성화인자 길항제 검색

Screening of Platelet Activating Factor(PAF) Antagonist from Medicinal Plants

  • 발행 : 1994.06.30

초록

The platelet activating factor (PAF) is a newly discovered chemical mediator, the chemical structure of which is 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine. Since PAF has potent and broad activities, its pathophysiological roles have received much attention. To develope a new PAF antagonist from medicinal plants, extracts of twenty medicinal herb were screened using PAF receptor binding, $[^{14}C]$ serotonin release and platelet aggregation.

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