Antineoplastic Effect of Extracts from Traditional Medicinal Plants and Various Plants

전통 약용식물 및 각종 식물의 항암효과에 대한 연구

  • Hyun, Jin-Won (Laboratory of Cell Biology,Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Lim, Kyoung-Hwa (Laboratory of Cell Biology,Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Shin, Jin-E (Laboratory of Cell Biology,Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Sung, Min-Sook (Laboratory of Cell Biology,Cancer Research Institute and Cancer Research Center, Seoul National University College of Medicine) ;
  • Won, Yong-Jin (Natural Products Research Institute, Seoul National University) ;
  • Kim, Yeong-Shik (Natural Products Research Institute, Seoul National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute, Seoul National University) ;
  • Chang, Il-Moo (Natural Products Research Institute, Seoul National University) ;
  • Woo, Won-Sick (Natural Products Research Institute, Seoul National University) ;
  • Paik, Woo-Hyun (Central Research Laboratories, Boryung Pharmaceutical Co., Ltd.) ;
  • Kim, Hyoung-Ja (Division of Chemistry, Korea Institute of Science and Technology) ;
  • Woo, Eun-Rhan (Division of Chemistry, Korea Institute of Science and Technology) ;
  • Park, Ho-Koon (Division of Chemistry, Korea Institute of Science and Technology) ;
  • Park, Jae-Gahb (Laboratory of Cell Biology, Cancer Research Institute and Cancer Research Center, Seoul National University)
  • 현진원 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 임경화 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 신진이 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 성민숙 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부) ;
  • 원용진 (서울대학교 천연물과학연구소) ;
  • 김영식 (서울대학교 천연물과학연구소) ;
  • 강삼식 (서울대학교 천연물과학연구소) ;
  • 장일무 (서울대학교 천연물과학연구소) ;
  • 우원식 (서울대학교 천연물과학연구소) ;
  • 백우현 (보령제약 주식회사 중앙연구소) ;
  • 김형자 (한국 과학기술연구원) ;
  • 우은란 (한국 과학기술연구원) ;
  • 박호군 (한국 과학기술연구원) ;
  • 박재갑 (서울대학교 의과대학 암연구소 및 암연구센타 세포생물학 연구부)
  • Published : 1994.06.30

Abstract

Antineoplastic activity against human gastric and colon carcinoma cell lines was measured in 100 extracts from 90 plants using MTT (3-[4,5-dimethyl thiazo-2-yl]-2, 5-diphenyl tetrazolium bromide) method. Four extracts from four plants have been reported to have antineoplastic effect. Extracts from remaining 86 plants failed to show significant cytotoxic effect at the concentration of less than $230\;{\mu}/ml$.

Keywords