Korean Journal of Pharmacognosy (생약학회지)
- Volume 25 Issue 1
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- Pages.1-10
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- 1994
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Herbal Drug Interactions Due to Alteration of Metabolism
- Woo, Won-Sick (Natural Products Research Institute, Seoul National University)
- Published : 1994.03.30
Abstract
The screening of 150 Chinese drugs which are most frequently prescribed in Korean traditional medicine showed that at least 30% of the drugs affected barbiturate-induced hypnosis. This effect was mainly attributable to the alteration of drug metabolism. Phytochemical works resulted in the isolation of furanocoumarins, lignans, sesquiterpenes and saponins as drug metabolism modifiers. The structure-activity relationship is discussed.
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