The Korean Journal of Pharmacology (대한약리학회지)
- Volume 30 Issue 2
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- Pages.255-260
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- 1994
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- 0377-9459(pISSN)
Influences of Free Fatty Acid on the Albumin Binding of Warfarin and Dansylsarcosine
Warfarin, Dansylsarcosine의 알부민결합에 미치는 유리지방산의 영향
- Bae, Jin-Woo (Department of Pharmacology, Medical College of Kon-Kuk University)
- 배진우 (건국대학교 의과대학 약리학교실)
- Published : 1994.09.30
Abstract
There are some reports about the influences of free fatty acids on the albumin binding of drugs. But they were concerned to the limited free fatty acids, mostly of azapropazone-warfarin bidning site bound drugs and determination of dissociation and association constants by stopped flow technique. These data were not enough to make conculsions for the general tendency of free fatty acid to albumin binding. Therefore the influence of various saturated fatty acids of