YAKHAK HOEJI (약학회지)
- Volume 38 Issue 6
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- Pages.800-805
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Enhancing Effect of the Combined Preparation Containing Antacid and Aceglutamide Aluminium on Defensive Factors in Chronic Ulcer Model of the Rat
흰쥐의 만성궤양모델에서 Aceglutamide aluminium를 함유한 복합제산제의 점막방어인자 증강작용
- Jang, Byeong-Su (R/D Center, Daewoong Pharm. Co. Ltd.) ;
- Yoo, Eun-Ju (R/D Center, Daewoong Pharm. Co. Ltd.) ;
- Park, Joon-Woo (R/D Center, Daewoong Pharm. Co. Ltd.) ;
- Yu, Young-Hyo (R/D Center, Daewoong Pharm. Co. Ltd.) ;
- Park, Myung-Hwan (R/D Center, Daewoong Pharm. Co. Ltd.)
- 장병수 ((주)대웅제약중앙연구소) ;
- 유은주 ((주)대웅제약중앙연구소) ;
- 박준우 ((주)대웅제약중앙연구소) ;
- 유영효 ((주)대웅제약중앙연구소) ;
- 박명환 ((주)대웅제약중앙연구소)
- Published : 1994.12.30
Abstract
Antacid(AM, 600 mg/kg=aluminium hydroxide, magnesium hydroxide, and simethicone with a ratio of 1 : 1 : 0.1) and aceglutamide aluminium(AGA, 263 mg/kg)-Effect of the combined preparation containing on the gastric mucosal hexosamine, sialic acid, and aluminium contents adhered to the gastric wall of the rat was investigated. Severe ulcers were produced in rats by injecting of
Keywords
- Antacid [$Al(OH)_3$, $Mg(OH)_2$, simethicone];
- Aceglutamide Aluminium;
- Hexosamine;
- Sialic acid;
- Anti-ulcer effect