약학회지 (YAKHAK HOEJI)
- 제38권5호
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- Pages.525-529
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
카리기난 유발 족부종법에 이용한 플루르비프로펜 겔의 항염증작용 평가
Antiinflammatory Activity of Flubiprofen Gel on Carrageenan-induced Edema
- Gil, Hyung-Jun (College of Pharmacy, Sung Kyun University) ;
- Lee, Jang-Won (College of Pharmacy, Sung Kyun University) ;
- Chi, Sang-Cheol (College of Pharmacy, Sung Kyun University)
- 발행 : 1994.10.30
초록
Antiinflammatory activity of an 1% flurbiprofen transdermal gel was evaluated using the carrageenan-Induced rat paw edema method. The application of 50 mg of the gel on the rat hind paw, at various time intervals from 0 to 24 hrs before the carrageenan injection, significantly inhibited edema formation in all groups of dosed rats, indicating that the antiinflammatory activitv was maintained up to 24 hrs after the transdermal application of the 1% flurbiprofen gel. The topical