YAKHAK HOEJI (약학회지)
- Volume 38 Issue 5
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- Pages.504-510
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Synthesis of 2-Aryl-5-benzoxazolepropionic Acid Derivatives as Antiinflammatory Agent
항염증제로서 2-아릴-5-벤즈옥사졸프로피온산 유도체의 합성
- Choi, Hong-Dae (Department of Chemistry, Dongeui University) ;
- Kowak, Yong-Sil (Department of Chemistry, Dongeui University) ;
- Geum, Dek-Hyun (Department of Chemistry, Dongeui University) ;
- Son, Byeng-Wha (Department of Chemistry, National Fisheries University of Pusan)
- Published : 1994.10.30
Abstract
A facile synthesis of 2-aryl-5-benzoxazolepropionic acid derivatives(1 0a-d), which are potent antiinflammatory agent, is reported. Methyl
Keywords
- 2-Aryl-5-benzoxazolepropionic acid;
- Antiiflammatory agent;
- Methyl ${\alpha}$-(p-hydroxyphenyl)propionate;
- Friedel-Craks reaction,;
- Metyl ${\alpha}$-chloro-${\alpha}$-(methylthio)acetate;
- Desulfurization;
- Formation of benzoxasole ring