약학회지 (YAKHAK HOEJI)
- 제38권2호
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- Pages.211-217
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Xanthine oxidase 활성 및 형전환에 미치는 구리이온의 영향
Effect of Copper ion on Xanthine Oxidase Activity and Type Conversion
- Huh, Keun (Dept. of Pharmacology, College of Pharmacy, Yeung-nam Univ.) ;
- Lee, Sang-Il (Dept. of Food & Nutrition, Kei-myung Junior College) ;
- Park, Jeen-Woo (Dept. of Biochemistry, College of Natural Science, Keyng-pook National Univ.)
- 발행 : 1994.04.30
초록
Copper intoxication and disturbance of copper metabolism induced various oxygen-derived free radicals related damages. The effect of copper ion on xanthine oxidase activity and type conversion of the enzyme which is concerned to generation of reactive oxygen species, was investigated, It was observed that xanthine oxidase activity was increased by addition of copper ion in the reaction mixture in proportional to the concentration of the metal ion until