약학회지 (YAKHAK HOEJI)
- 제38권1호
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- Pages.86-90
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- 1994
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
7,8-Dioxo-A-norerythrinan의 합성
Synthesis of 7,8-Dioxo-A-norerythrinan
- Bae, Ki-Hwan (College of Pharmacy, Chungnam University) ;
- Seo, Won-Jun (College of Pharmacy, Chungnam University)
- 발행 : 1994.02.28
초록
7,8-Dioxo-A-norerythrinan (A) was synthesized from acid catalyzed cyclization of 6a-hydroxv-1-(2-phenylethyl)-octahydrocyclo-penta[b] pyrrole-3a-carboxylic acid ethyl ester (B) with concomitant deethoxycarbonylation. The intermediate (B) was a hydroxylated compound of N-acyliminium (C). The unstable pyrrolinium (C) was prepared from oxalylation of the enamine of phenethylamine and ethyl 2-oxocyclopentanecarboxylate.
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