약물 유도성 낙엽상 천포창 2예

Two Cases of Drug-Induced Pemphigus Foliaceus

저자들은 최근 임상양상, 병리조직학적 검사 그리고 면역형광 검사소견상 약물유도성 낙엽상 천포창으로 진단된 2례를 경험하고 이를 문헌고찰과 함께 보고한다.

Drug-induced pemphigus has been well recognized in recent years. It has been generally believed to be a benign disease responding to withdrawal of the drug or to treatment with a short course of oral corticosteroids. We report herein two cases of drug-induced pemphigus foliaceus. The patients had erosive and eczematoid patches chiefly on anterior chest abdomen, flank and back The diagnosis of the two patients were confirmed by immunofluorescence studies. In these two patients, one was recognized as a penicillamine-induced pemphigus foliaceus, and the other was recognized as a rifampicin-induced pemphigus foliaceus.