Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Studies on the pathogenesis of group A avian rotavirus infection in turkeys

Group A 조류 로타 바이러스의 병원성에 관한 연구

  • Kang, Shien-young (Department of Veterinary Medicine, College of Agriculture, Chungbuk National University) ;
  • Nagaraja, Kakambi V. (Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota) ;
  • Newman, John A. (Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota)
  • 강신영 (충북대학교 농과대학 수의학과) ;
  • ;
  • Received : 1993.01.05
  • Published : 1993.04.30
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Abstract

Commercial turkey poults not previously exposed to avian rotavirus were inoculated orally with the virus alone or in combination with E coki serotype 078 at 1, 7, 14 and 21 days of age. Turkey poults of 1, 7 and 14 days of age were susceptible to infection despite the presence of maternal antibodies against avian rotavirus in their serum. However, turkey poults at 21 days of age were less susceptible compared to those ages 1, 7 and 14 days. The clinical signs in poults of all ages were mild. Viral antigens were demonstrated in the mature villous epithelial cells of the duodenum, jejunum and ilem. Histopathological lesions were characterized by vacuolation of the epithelial cells and heterophil infiltration in infected turkey poults. A significant difference in D-xylose absorption was observed between control and rotavirus infected groups at 1 and 3 days post-infection in 14 days old turkey poults.

조류 로타바이러스 감염 음성인 1일령, 7일령, 14일령 그리고 21일령된 칠면조에 조류 로타바이러스를 인공감염시킨 후 소장에서의 바이러스의 분포, 배출 그리고 소장의 흡수기능을 조사하였다. 1일령, 7일령 그리고 14일령의 칠면조는 조류 로타바이러스에 대한 혈중모체이행항체의 존재에도 불구하고 로타바이러스 감염에 민감하였다. 인공감염된 칠면조는 경미한 임상증상을 보였으며 십이지장, 공장 그리고 회장의 성숙된 용모상피세포에서 바이러스가 검색되었다. 병리조직학적인 소견으로서는 상피세포에 공포가 형성되었으며 호중구의 침윤이 관찰되었다. 조류 로타바이러스에 인공감염된 14일령 칠면조에서 감염후 1일과 3일에 D-xylose흡수기능은 대조군과 비교하였을 때 유의성이 인정되었다.

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