BLOOD CHEMICAL ALTERATIONS IN EXPERIMENTAL Setaria cervi INFECTION IN RABBITS

Adult male and female Setaria cervi worms were implanted in the peritoneal cavity of rabbits to develop microfilaraemia. These infected rabbits revealed non-significant rise in total protein, significant reduction in albumin content and albumin-globulin ratio and significant increase in globulin and total bilirubin. The levels of total cholesterol, blood urea nitrogen and urea in blood were elevated from day 20 to 40, 25 to 70 and 30 to 70 respectively whereas, uric acid remained high from day 25 to 50 and creatinine from 15th day to 50th day of worm implantation. Biochemical changes suggested the involvement of liver and kidney in the infected rabbits.