Journal of Yeungnam Medical Science
- 제10권1호
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- Pages.68-76
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- 1993
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- 2799-8010(eISSN)
임신성 고혈압 환자에서 적혈구교체의 지표로서 일산화탄소 혈색소와 혈청 철의 임상적 의의
Increased Carboxyhemoglobin and Serum Iron Concentration as an Indicator of increased Red Cell Turnover in Preeclampsia
- 김상헌 (영남대학교 의과대학 산부인과학교실) ;
- 이광희 (영남대학교 의과대학 산부인과학교실) ;
- 김미숙 (영남대학교 의과대학 산부인과학교실) ;
- 이영기 (영남대학교 의과대학 산부인과학교실) ;
- 박윤기 (영남대학교 의과대학 산부인과학교실) ;
- 이태형 (영남대학교 의과대학 산부인과학교실) ;
- 이승호 (영남대학교 의과대학 산부인과학교실)
- Kim, Sang-Heon (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Lee, Kwang-Hee (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Kim, Mi-Sook (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Lee, Young-Gi (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Park, Yoon-Kee (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Lee, Tae-Hyung (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University) ;
- Lee, Sung-Ho (Department of Obstetrics and Gynecology College of Medicine, Yeungnam University)
- 발행 : 1993.06.30
초록
1992년 10월 1일부터 1993년 3월 31월까지 영남대학교 의과대학 부속병원 산부인과에 입원하여 만삭분만한 정상산모 35명을 대조군으로, 경증 자간전증 환자 23명을 대상군으로 일산화탄소혈색소와 혈청 철의 농도를 측정하여 다음과 같은 결과를 얻었다. 혈청철의 농도는 임신성 고혈압 환자군에서
Pregnancy induced hypertension is multifaceted syndrome with variable involvement of several key organ systems, so sensitive and specific laboratory tests for predicting severity and prognosis, and early diagnosis of this disease are required. Because heme catabolism results in equimolar production of carboxyhemoglobin, iron and bilirubin, a concomittant rise of these parameters would provide confirmation of increased heme catabolism. Microangiopathic hemolytic anemia may occurs in severe preeclampsia, but it is not known whether increased red cell turnover occurs with mild preeclampsia as complication. The purpose of this study was to confirm that increased heme catabolism also occurs in patients with mild preeclampsia. The analysis of data was done on 23 cases with mild preeclampsia and 35 normal pregnant women, who were admitted to Yeungnam University Hospital from October 1992 to March 1993. The results were as follows. 1. The mean antepartum serum iron concentration was significantly higher in the group with mild preeclampsia(