Journal of Periodontal and Implant Science
- Volume 23 Issue 3
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- Pages.647-658
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- 1993
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- 2093-2278(pISSN)
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- 2093-2286(eISSN)
TOPICAL APPLICATION OF TETRACYCLINE GEL IN SCALING AND ROOT PLANING
치석제거 및 치근활택술 시에 테트라싸이클린 젤의 국소적 도포
- Han, Soo-Boo (Department of Periodontology, School of Dentistry, Seoul National University) ;
- Lee, Jae-Il (Department of Oral Pathology, School of Dentistry, Seoul National University) ;
- Heo, Jeong-Mi (Department of Periodontology, School of Dentistry, Seoul National University) ;
- Chang, Mee-Kyung (Department of Periodontology, School of Dentistry, Seoul National University) ;
- Shim, Chang-Koo (Department of Phamacetics, College of Pharmacy, Seoul National University) ;
- Lee, Chul-Woo (Department of Periodontology, School of Dentistry, Seoul National University)
- 한수부 (서울대학교 치과대학 치주과학 교실) ;
- 이재일 (서울대학교 치과대학 구강병리학 교실) ;
- 허정미 (서울대학교 치과대학 치주과학 교실) ;
- 장미경 (서울대학교 치과대학 치주과학 교실) ;
- 심창구 (서울대학교 약학대학 제약학과) ;
- 이철우 (서울대학교 치과대학 치주과학 교실)
- Published : 1993.11.30
Abstract
The purpose of this study is to examine the influence of 5% tetracycline(Tc) gel on healing of gingival tissue and change of diseased root surface when used with nonsurgical procedure. 7 patients with advanced periodontitis were received thorough scaling and root planning, followed by saline irrigation on 10 randomly selected control teeth and Tc gel application for 5 minutes with specifically designed plastic instrument of 10 test teeth in contralateral side. At 0, 1, 7, 14, and 21 days after treatment, biopsy and extraction were carried out. At day 7, Tc group showed decreased inflammation and delayed proliferation of pocket epithelium in comparison with control group which was continued for all experimental days. Scanning electron microscopic finding revealed demineralized and cleaned root surface with exposed dentinal tubules in Tc gel group. In the present study, clinically successful result is expected with combined use of nonsurgical periodontal therapy and intrapocket application of Tc gel.