비타민 D$_3$와 인산칼슘의 토끼 대퇴골 골절치유 효과에 대한 골수강내 정맥 조영술

Intraosseous Phlebography for Determination of the Effect of Vitamin D$_3$ and Calcium Phosphate on Fractured Bone Healing in Rabbit

  • 엄기동 (서울대학교 수의과대학) ;
  • 성재기 (서울대학교 수의과대학)
  • 발행 : 1993.12.01

초록

Intraosseous phlebography was performed to determine the healing effect of the dosing treated with vitamin-D$_3$ and/or calcium phosphate on the fractured bone in male rabbits. Femoral shafts of 16 adult male rabbits were fractured and these animals were divided into 3 treated groups and 1 control group l. The 1st treated group of rabbits was dosed with vitamin-D$_3$(VD), the 2nd treated group of rabbits was given calcium phosphate(CP), and the 3.d treated group of rabbits received vitamin-D$_3$ and calcium phosphate. The control group of rabbits was dosed with saline alone. Radiographs were taken weekly in each rabbit over 6 weeks period and the results obtained were as follows. 1. Sinusoidal vein was visualized at 3rd week in eve animal received CP and VC, at 5 week in animals received VD and in control animals. 2. Main nutrient vein was observed more clearly in treated groups than in control group of animals. 3. These results indicate that venous reconstruction of the fractured bone in groups of rabbits received CP and VC was earlier and more complete than those of other groups of rabbits. 4. Therefore, intraosseous phlebography is suitable for determination of the bone healing effect of vitamin-D$_3$ and/or calcium phosphate in femoral fractured rabbits.

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