The Korean Journal of Nuclear Medicine (대한핵의학회지)

The Korean Society of Nuclear Medicine (대한핵의학회)
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Cold Lesions in $^{99m}Tc$-MDP Bone Scans of Patients with Skeletal Metastases

$^{99m}Tc$-MDP 골스캔에서 냉소로 나타난 전이 암의 분석

  • Choi, C.W. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Yang, H.I. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Bae, S.K. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Lee, D.S. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Sohn, I. (Department of internal Medicine, Kangnam General Hospital) ;
  • Chung, J.K. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Lee, M.C. (Department of Nuclear Medicine, Seoul National University Hospital) ;
  • Koh, C.S. (Department of Nuclear Medicine, Seoul National University Hospital)
  • 최창운 (서울대학교병원 핵의학과) ;
  • 양형인 (서울대학교병원 핵의학과) ;
  • 배상균 (서울대학교병원 핵의학과) ;
  • 이동수 (서울대학교병원 핵의학과) ;
  • 손인 (지방공사 강남병원 내과) ;
  • 정준기 (서울대학교병원 핵의학과) ;
  • 이명철 (서울대학교병원 핵의학과) ;
  • 고창순 (서울대학교병원 핵의학과)
  • Published : 1993.06.15
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Abstract

The present study was purposed to evaluate the incidence and the characteristics of metastatic "cold" lesions in $^{99m}Tc$-MDP bone scans of adult patients with solid malignancies. There were 29 cold lesions in 24 patients. The incidence of cold lesions was about 1% of total cases of bone scans for the patients with malignancy, or 2.5% of cases with bone metastases. Th primary sites of malignancies were lung (four cases), uterine cervix (three cases), kidney, nasopharynx, thyroid, urinary bladder, prostate, lymphoma (two cases each other), liver, breast and others (one case each other). But the relative incidence of cold lesion in lung cancer and breast cancer was low. The most frequent site of cold lesion was spine, and pelvis, skull and rib were followed. The incidence of cold lesion was related to the regional incidence of bone metastases. The size of the cold lesions was greater than that of the hot. There were six cases of single cold lesion without any other abnormalities and two cases of cold lesion which were initially hot. So it should be considered that bone metastases might be presented as cold lesions in bone scan.

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