Antitumor Activity of Lactobacillus casei against Sarcoma 180 and Lewis Lung Carcinoma in Mice

생쥐에서 Sarcoma 180 및 Lewis Lung Carcinoma에 대한 Lactobacillus casei의 항암 효과

  • Published : 1993.06.01

Abstract

Antitumor activity of Lactobacillus casei YIP 9018(LC9018) was studied in mice by using sarcoma 180(S-180) and Lewis lung carcinoma (3LL). Following the eatablishment of in vivo tumor models such as ascites form S-180, solid form S-180 and 3LL for estimating antitumor activity of Lactobacilli, optimal dose and injection route of heat-killed LC9018 for supperssion of local tumor were examined. Administration of 100ng/mouse of LC9018 significantly inhibited the growth of ascites form S-180, solid form S-180 and 3LL.

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