Toxicological Research

Korean Society of Toxicology & Korea Environmental Mutagen Society (한국독성학회)
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A STUDY ON THE RECOMBINANT GRANULOCYTEMACROPHAGE COLONY STIMULATING FACTOR (LBD-005) FOR PRIMARY SKIN IRRITATION IN RABBITS

  • Park, Jong-Il (Toxicology Research Center Korea Research Institute of Chemical Technology) ;
  • Kim, Sung-Hoon (Toxicology Research Center Korea Research Institute of Chemical Technology) ;
  • Roh, Jung-Koo (Toxicology Research Center Korea Research Institute of Chemical Technology)
  • Published : 1993.06.01
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Abstract

LBD-005, a newly developed recombinant granulocyte-macrophage colony stimulating factor, was tested for primary skin irritation in male New Zealand White rabbits. In the primary skin irritation test, LBD-005 was applied to intact and abraded skins for 24 hours. Primary irritation index was "0" in test and control sites of all animals' thus LBD-005 was evaluated as a non-irritatant on the basis of the criteria of Draize et al. (1994).l. (1994).

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References

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