YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Total Synthesis of 11-Deoxy-$\beta$-rhodomycinone Antitumor Antibiotics

항암항생제 11-Deoxy-$\beta$-rhodomycinone의 합성

  • 노영쇠 (전북대학교 자연과학대학 화학과) ;
  • 강혼수 (미원중앙연구소 제3연구실) ;
  • 신홍식 (전북대학교 자연과학대학 화학과)
  • Published : 1993.12.01
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Abstract

Methyl 3-[(phenylsulfonyl)methyl]-1, 4, 8-trimethoxy-2-naphthoate(7) preparad by 3 steps was condensed with 5-ethyl-2-cyclohexen-1-one(8) to afford the teracyclic aromatic ring system compound 10, which was stepwise converted into the precursor of 11-Deoxy-$\beta$-rhodomycinone by means of various functional groups transformation.

Keywords

References

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