YAKHAK HOEJI (약학회지)
- Volume 37 Issue 5
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- Pages.427-436
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- 1993
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Pharmacokinetics of Omeprazole from Rectal Suppositories
오메프라졸 함유 직장좌제의 약물속도론적 연구
Abstract
The pharmacokinetics and relationship between in vitro dissolution and in vivo fraction absorbed were investigated after intravenous(iv) injection of omeprazole(OMZ), oral administration of OMZ capsules and rectal administration of 8 types of suppositories. The plasma concentration of OMZ (C
Keywords
- Omeprazole;
- Witepsol H15;
- PEG 4000;
- Pharmacokinetics;
- Bioavailability;
- Avoidance fraction of first pass metabolism