YAKHAK HOEJI (약학회지)
- Volume 37 Issue 3
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- Pages.247-253
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- 1993
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- 0377-9556(pISSN)
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- 2383-9457(eISSN)
Synthesis of Naftifine-Related Allylamine as a Potential Antimycotics
항진균제 Naftifine 구조와 관련된 알릴아민류의 합성
- Kim, Wook (Jin Yang Pharmaceutical Co.) ;
- Park, Eun-Ju (College of Pharmacy, Chonnam National University) ;
- Seo, Hee-Kyong (College of Pharmacy, Chonnam National University) ;
- Shin, Boo-Ahn (College of Pharmacy, Chonnam National University) ;
- Choi, Bo-Gil (College of Pharmacy, Chonnam National University) ;
- Chung, Byung-Ho (College of Pharmacy, Chonnam National University)
- 김욱 (진양제약) ;
- 박은주 (전남대학교 약학대학) ;
- 서희경 (전남대학교 약학대학) ;
- 신부안 (전남대학교 약학대학) ;
- 최보길 (전남대학교 약학대학) ;
- 정병호 (전남대학교 약학대학)
- Published : 1993.06.01
Abstract
Eight new derivatives of allylamine which are related to naftifine and expected to have antifungal activity were synthesized. Schiff base 2a-2d and 2'e-2'h were obtained by conventional methods using trans-cinnamylamine or trans-cinnamaldehyde. The reduction of azomethine linkage with NaBH
Keywords
- trans-Cinnamylamine;
- trans-cinnamaldehyde;
- methoxybenzaldehyde;
- salicylaldehyde;
- piperonylamine;
- p-dimethylaminobezaldehyde;
- heptylamine;
- 2-amino-6-methylbenzthiazole;
- 2-amino-6-methoxybenzthiazole