HMG-CoA환원효소의 저해제로서 2-치환-벤즈이미다졸 유도체의 합성

Synthesis of 2-Substituted Benzimidazole Derivatives as Potential HMG-CoA Reductase Inhibitors

Designed system, in which the $\beta$-hydroxy-$\delta$-lactone moiety is connected to benzimdazole ring by ethylene bridge, was propared from 2-sustd. benzimidazole as a potential HMG-CoA reductase inhibitor.