Archives of Pharmacal Research
- 제16권4호
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- Pages.339-342
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- 1993
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Antiviral Activity of Triterpenoid Derivatives
- Ryu, Shi-Yong (Korea Research Institute of Chemical Technology) ;
- Lee, Chong-Kyo (Korea Research Institute of Chemical Technology) ;
- Ahn, Jong-Woong (Korea Research Institute of Chemical Technology) ;
- Lee, Seung-Ho (Korea Research Institute of Chemical Technology) ;
- Zee, Ok-Pyo (Colllege of Pharmacy, SungkyunKwan University)
- 발행 : 1993.12.01
초록
3-Oxo or/and 11-oxo derivatives of natural 3-hydroxy triterpense, i.e., 3-oxoursolic acid la, 11-oxoursolic acid lb, 3, 11-dioxoursolic acid ic, 3-oxobetulinic acid lla and 3-oxopomolic acid Via were exhibited to show an increased anti-HSV-1 activity in vitro, four to ten times as much as corresponding parent 3-hydroxy compounds.
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