Archives of Pharmacal Research
- Volume 16 Issue 4
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- Pages.318-321
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- 1993
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Cyanoacetic Acid Hydrazide in Heterocyclic Synthesis: A New Route for the Synthesis of Several Annelated Pyran Derivatives
- Eldin, Sanaa M. (National Research Center) ;
- El-Din, Asmaa A. Magd (National Research Center) ;
- Basyouni, Wahid M. (National Research Center)
- Published : 1993.12.01
Abstract
Cyanoaccetic acid hydrazide reacted with some 2-pyrazolin-5-one, isoxazol-5-one and 2-thiazolin-4-one and their ylidene derivatives to yield several new annelated pyran heterocycles. Structures wre established on the basis of elementary analyses and spectral data studies in addition to synthesis via other routes.
Keywords
- 2-Pyrazolin-5-ones;
- 2-Thiazolin-4-ones;
- lsoxazolin-5-ones;
- Pyrano[2,3-c]pyrazoles;
- Pyrano[2,3-c]isoxazooles;
- Pyrano[2,3-d]thiazoles