Journal of Ginseng Research

  • 제17권2호
  • /
  • Pages.127-130
  • /
  • 1993
  • /
  • 1226-8453(pISSN)
  • /
  • 2093-4947(eISSN)
고려인삼학회 (The Korean Society of Ginseng)
권호 표지

고려홍삼의 지용성 분획에 의한 세로토닌 방출의 억제

Inhibition of Perotonin Release by Lipophilic Fraction From Korean Red Ginseng

  • Rhee, Man-Hee (Department of Biochemical Pharmacology, Korea Ginseng & Tobacco Research Institute) ;
  • Park, Kyeong-Mee (Department of Biochemical Pharmacology, Korea Ginseng & Tobacco Research Institute) ;
  • Park, Hwa-Jin (Department of Biochemical Pharmacology, Korea Ginseng & Tobacco Research Institute) ;
  • Nam, Ki-Yeul (Department of Biochemical Pharmacology, Korea Ginseng & Tobacco Research Institute) ;
  • Park, Ki-Hyun (Department of Biochemical Pharmacology, Korea Ginseng & Tobacco Research Institute)
  • 발행 : 1993.08.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Lipophilic Fraction (LF) from Panax ginseng C.A. Meyer strongly inhibited human platelet aggregations induced by thrombin. When platelets were prelabeled with 5-hydroxy[G-$^3$H]-tryptamine (serotonin) and then stimulated by thrombin, LF inhibited the release of serotonin in a dose-dependent manner. From this result, we suggest that LF have antiplatelet and antimigraine functions by inhibiting the release of serotonin.

키워드