Journal of Pharmaceutical Investigation
- Volume 23 Issue 1
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- Pages.19-26
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- 1993
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- 2093-5552(pISSN)
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- 2093-6214(eISSN)
Alginate Beads as Controlled Release Polymeric Drug Delivery System
Alginate Bead를 이용한 고분자 약물의 제어방출형 약물수송체
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Hwang, Sung-Joo
(College of Pharmacy, Chungnam National University) ;
- Rhee, Gye-Ju (College of Pharmacy, Chungnam National University) ;
- Jo, Hang-Bum (College of Pharmacy, Chungnam National University) ;
- Lee, Ki-Myung (College of Pharmacy, Chungnam National University) ;
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Kim, Chong-Kook
(College of Pharmacy, Seoul National University)
- Published : 1993.03.20
Abstract
The purpose of this paper is to explore the possible applicability of alginate beads as an oral controlled release system of polymeric drugs. Cellulase was used as a model polymeric drug. The release of cellulase from alginate beads was moderately affected by the ratio of cellulase to sodium alginate and strongly affected by
Keywords
- Alginate bead;
- Cellulase;
- Polymeric drug;
- Polypeptide drug;
- Controlled release;
- Oral delivery system