Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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The Polysaccharide Fraction of Artemisia Species(I)

Artemisia속 생약의 다당류 분획 연구 (I)

  • Lee, Kang-Ro (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Zee, Ok-Pyo (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Kwak, Jong-Hwan (Department of Pharmacy, College of Pharmacy, Sungkyunkwan University) ;
  • Kim, Yeong-Shik (Natural Products Research Institute, Seoul National University) ;
  • Park, Ho-Kun (Division of Chemistry, Korea Institute of Science and Technology) ;
  • Koo, Kyong-Ah (Department of Microbiology, College of Natural Sciences, Inje University) ;
  • Youn, Hyun-Joo (Department of Microbiology, College of Natural Sciences, Inje University)
  • Published : 1993.12.30
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Abstract

Polysaccharides fractions from the leaves of Artemisia selengensis$(ASP_1)$ and Artemisia iwayomogi$(ASP_1)$ were extracted and purified by Sephadex gel filtration and DEAE-Sephadex ion exchange chromatographies. Both $ASP_1$ and $AIP_1$ fractions were tested for their effects on the spleen cell culture in vitro. Both $ASP_1$ and $AIP_1$ fractions allow growth of spleen cells up to 3 months in culture, suggesting the immunoregulatory activities of those polysaccharide fractions. The molecular weights of $ASP_1$ and $ASI_1$ fractions were found to be about 2,500 daltons by Sephadex gel filtration chromatography using standard dextrans. Both $ASP_1$ and $AIP_1$ fractions were composed of glucose, xylose and galactose.

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