Journal of the Korean Academy of Child and Adolescent Psychiatry
- 제3권1호
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- Pages.46-55
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- 1992
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- 2233-9183(eISSN)
발달성언어장애아(發達性言語障碍兒)의 단일광자방출전산화단층촬영(單一光子防出電算化斷層撮影) 소견(所見)에 관한 연구
THE SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY FINDINGS IN DEVELOPMENTAL LANGUAGE DISORDERS
- Park, Jin-Seng (Department of Psychiatry, Seoul National University(Division of Child and Adolescent Psychiatry)) ;
- Cho, Soo-Churl (Department of Psychiatry, Seoul National University(Division of Child and Adolescent Psychiatry)) ;
- Lee, Myung-Chul (Department of Internal Medicine, Seoul National University(Division of Nuclear Medicine))
- 발행 : 1992.12.31
초록
발달성언어장애는 학령기 아동에서 약
The pathophysiology of developmental language disorder is a highly controversial matter. In order to investigate the neural mechanisms involved in developmental language disorders, the authors studied three dimensional regional cerebral blood flow(rCBF) using Tc-99mH-MPAO in 42 children with developmental language disorders. The results are summarized as follows : 1) 61.9% (26/42) of this series revealed decreased perfusion in SPECT. 2) Regions of hypoperfusion were seen in cerebral cortex(47.6%, 20/42), thalamus(33.3%, 14/42), basal ganglia(11.9%, 5/42) and cerebellum(7.1%, 3/42). This study suggests that developmental language disorder could be due to specific functional impairment of the local brain regions which could not detected by conventional investigations such as brain CT or EEG.