The Korean Journal of Pain

The Korean Pain Society (대한통증학회)
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Intravenous Regional Administration of Prostaglandin E1 for the Treatment of Buerger's Disease

Buerger법 치료를 위한 국소 정맥내 Prostaglandin E1 주입

  • Choe, Huhn (Department of Anesthesiology, Chonbuk National University Medical School) ;
  • Kim, Dong-Chan (Department of Anesthesiology, Chonbuk National University Medical School) ;
  • Han, Young-Jin (Department of Anesthesiology, Chonbuk National University Medical School)
  • 최훈 (전북대학교 의과대학 마취과학교실) ;
  • 김동찬 (전북대학교 의과대학 마취과학교실) ;
  • 한영진 (전북대학교 의과대학 마취과학교실)
  • Published : 1992.05.23
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Abstract

Buerger's disease is a chronic occlusive arterial disease in which a non-arteriosclerotic lesion involves medium-sized arteries, veins, and nerves of the distal leg or arm. Sympathetic interruption is indicated to improve blood flow to the involved extremity, although sympathetic blockade can provide temporally relief of vasospasm and pain. Chemical or surgical sympathectomy has been performed for this purpose and intravenous regional sympathetic block(IRSB) is an alternative. Guanethidine or reserpine has been administered for IRSB. Intraarterial or intravenous systemic administration of prostaglandin E1(PGE1) has been recommended for the treatment of Buerger's disease. We used PGE1 for intravenous regional administration as an IRSB with results as good as that of intraarterial injection. The advantages of the method include that it is less expensive than systemic administration, less invasive than intra-arterial injection, and simple in technical application.

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