Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지

Combined Radiation Therapy and Hyperthermia in Management of N3(AJCC-UICC) Metastatic Neck Nodes

N3(AJCC-UICC) 전이성 경부 임파절의 방사선 및 온열 병행요법

  • Lee Chang-Geol (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Kim Gwi-Eon (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Seong Jin-Sil (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Suh Chang-Ok (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Loh John-Kyu (Department of Radiation Oncology, Yonsei University College of Medicine) ;
  • Kim Byung-Soo (Yonsei Cancer Center) ;
  • Park Kyung-Ran (Department of Radiation Oncology, Yonsei University Wonju College of Medicine) ;
  • Lee Jong-Young (Department of Radiation Oncology, Yonsei University Wonju College of Medicine) ;
  • Hong Won-Pyo (Department of Otolaryngology, Yonsei University College of Medicine) ;
  • Park Cheong-Soo (Department of General Surgery, Yonsei University College of Medicine) ;
  • Kim Soo-Kon (Department of Radiation Oncology, Cheonju Presbyterian Hospital)
  • 이창걸 (연세대학교 의과대학 치료방사선과학교실) ;
  • 김귀언 (연세대학교 의과대학 치료방사선과학교실) ;
  • 성진실 (연세대학교 의과대학 치료방사선과학교실) ;
  • 서창옥 (연세대학교 의과대학 치료방사선과학교실) ;
  • 노준규 (연세대학교 의과대학 치료방사선과학교실) ;
  • 김병수 (연세대학교 의과대학 연세암센터) ;
  • 박경란 (연세대학교 원주의과대학 치료방사선과학교실) ;
  • 이종영 (연세대학교 원주의과대학 치료방사선과학교실) ;
  • 홍원표 (연세대학교 의과대학 이비인후과학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실) ;
  • 김수곤 (전주예수병원 치료방사선과)
  • Published : 1992.06.01
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Abstract

In order to improve the control of large unresectable(>6cm) and fixed N3(TNM-UICC) metastatic neck nodes, local hyperthermia(HT) has been combined with radiation therapty (RT) in Yonsei cancer center. From April 1985 to april 1988, a total of 18 patients of head and neck cancer with metastatic large unresectable and fixed cervical neck nodes who underwent combined RT and HT were analyzed. Of 18 patients, complete response rate was 39% (7 pt.) partial response 39% (7 pt.) and overall response rate was 78%. Acute side effects of these combined modalities were found in 8 patients and which were mainly cutaneous reaction such as erythema, dry and moist desquamation but recovered spontaneously in all patients after treatment. Factors of maximum tumor temperature above $43^{\circ}\C$ and MDF(multiple daily fractionation) showed more favorable response rate but not statistically sinificant. Two year actuarial survival rate of all patients was 35.4%.

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