상악골에 발생한 악성섬유성조직구종

MALIGNANT FIBROUS HISTIOCYTOMA OF THE MAXILLA ; REPORT OF A CASE

  • 류선열 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 박석인 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 이진환 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 정무강 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 정종철 (전남대학교 치과대학 구강악안면외과학교실) ;
  • 최홍란 (전남대학교 치과대학 구강병리학교실)
  • Ryu, Sun-Youl (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Park, Suk-In (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Lee, Jin-Hwan (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Chung, Mu-Gang (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Chung, Jong-Chull (Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Chonnam National University) ;
  • Choi, Hong-Ran (Dept. of Oral Pathology, School of Dentistry, Chonnam National University)
  • 발행 : 1992.03.31

초록

우측 협부의 종창과 압통을 주소로 내원한 59세의 여자 환자에서 방사선 소견상 우측 상악골의 광범위한 골파괴상이 나타났고 조직생검에서 MFH로 진단되었다. 치료는 술전과 술후에 SWOG외 CY-VA-DIC요법을 변형시킨 화학요법과 총 40Gy의 $^{60}Co$ 방사선요법 그리고 우측 상악골전적출술의 삼자병용요법을 시행하였다. 술후 2년이 경과된 현재까지 재발이나 전이 등의 소경은 관찰되지 않고 있으며 환자의 예후에 대하여 주의 깊은 관찰을 계속하고 있다.

Malignant fibrous histiocytoma rarely occurs in the jaws. A case of malignant fibrous histiocytoma originated from the maxillary sinus is reported with review of literature. A 59-year-old woman visited the Chonnam University Hospital in March, 1990, with chief complaint of swelling and tenderness in the right cheek. Radiographic findings revealed wide destruction of the maxilla. The biopsy taken from the maxilla showed histopatholgic findings of malignant fibrous histiocytoma. Accordingly the patient received preoperative and postoperative anticancer chemotherapy by the modified CY-VA-DIC protocol of the Southwest Oncology Group (SWOG). Preoperative and postoperative radiotherapy were also given to her in total 40Gy of $^{60}Co$ And she underwent radical resection of the maxilla. No evidence of recurrence or metastasis was shown for 2-year period of postoperative follow up.

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