Maxillofacial Plastic and Reconstructive Surgery

Korean Association of Maxillofacial Plastic and Reconstructive Surgeons (대한악안면성형재건외과학회)
권호 표지

AN EXPERIMENTAL STUDY OF THE EFFECTS OF BONE WAX ON THE MOUSE FEMORAL BONE DEFECTS

백서 대퇴골 결손부에 매식된 밀랍지혈제의 조직반응에 관한 실험적 연구

  • kim, Jang-Yun (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
  • Han, Kyung-Su (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
  • Um, In-Woong (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Wonkwang University) ;
  • Chung, Ho-Yong (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Wonkwang University)
  • 김장연 (원광대학교 치과대학 구강악안면외과학 교실) ;
  • 한경수 (원광대학교 치과대학 구강악안면외과학 교실) ;
  • 엄인웅 (원광대학교 치과대학 구강악안면외과학 교실) ;
  • 정호용 (원광대학교 치과대학 구강악안면외과학 교실)
  • Published : 1992.09.30
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Abstract

This study was to designed to evaluate the reactions of mouse femoral bone to bone wax. In sixteen mice with a strain of I. C. R. mouse weighed approximately 300 to 850g 2.0~2.0mm sized bone defects were created by drilling. Half of mice were inserted by bone wax and the remainder serving as control without bone wax application. The mice were sacrificed 1, 2, 6, 8 weeks after operation and block specimens were prepared for light microscopy examination. The results obtained were as follows. 1. Histologic features of tissue reaction to bone wax were the presence of inflammatory cell infiltration and multinucleated giant cell. 2. Bone ear healing from the created margin were markedly impaired by the application of bone wax 3. New bone formation was markedly decreased in bone wax application.

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