The Journal of Korean Academy of Prosthodontics (대한치과보철학회지)

The Korean Academy of Prosthodonitics (대한치과보철학회)
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AN IN VITRO STUDY ON CELLULAR RESPONSE OF SEVERAL DENTURE BASE RESINS

수종 의치상 레진의 세포반응에 관한 연구

  • Jun Chul-Oh (Department of Prosthodontics, College of Dentistry, Chonnam National University) ;
  • Vang Mong-Sook (Department of Prosthodontics, College of Dentistry, Chonnam National University)
  • 전철오 (전남대학교 치과대학 보철학교실) ;
  • 방몽숙 (전남대학교 치과대학 보철학교실)
  • Published : 1992.09.01
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Abstract

The present study quantitates the in vitro cytotoxicity of a variety of denture base acrylic resins using cell culture techniques combined with image analysis to measure nuclear area and DNA contents. In this study, a comparison was made among direct curing, heat curing and microwave curing resins. The results obtained from this study were as follows : 1. Morphologically, cell process and nucleus became prominent but macroscopic difference according to the resins were nit observed. In addition, increased cellular density around the specimen were observed. 2. In DNA contents measurements, $S-G_2M$ phase cell was 15.47%, 14.58% in control and heat curing resin on 1st day and the others group $21.39\sim33.36%$ were measured. 3. Nuclear area and DNA contents were increased on 3rd day except DNA content of the microwave curing resin group. These results suggest that denture base acrylic resins stimulate gingival fibroblasts in vitro, especially stimulation of direct curing resin is larger and longer than the others.

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