건강한 일부 도시지역 주민의 혈중 연 및 zinc protoporphyrin 농도

The levels of blood lead and zinc protoporphyrin for healthy urban population in Korea

  • 김동일 (동아대학교 의과대학 예방의학교실 및 산업의학연구소) ;
  • 김용규 (동아대학교 의과대학 예방의학교실 및 산업의학연구소) ;
  • 김정만 (동아대학교 의과대학 예방의학교실 및 산업의학연구소) ;
  • 정갑열 (동아대학교 의과대학 예방의학교실 및 산업의학연구소) ;
  • 김준연 (동아대학교 의과대학 예방의학교실 및 산업의학연구소) ;
  • 장형심 (동아대학교 의과대학 소아과학 교실) ;
  • 이영호 (동아대학교 의과대학 소아과학 교실) ;
  • 최안홍 (동아대학교 의과대학 소아과학 교실)
  • Kim, Dong-Il (Department of Preventive Medicine and The Industirial Medicine Research Institute College of Medicine, Dong-A University) ;
  • Kim, Yong-Kyu (Department of Preventive Medicine and The Industirial Medicine Research Institute College of Medicine, Dong-A University) ;
  • Kim, Jung-Man (Department of Preventive Medicine and The Industirial Medicine Research Institute College of Medicine, Dong-A University) ;
  • Jung, Kap-Yull (Department of Preventive Medicine and The Industirial Medicine Research Institute College of Medicine, Dong-A University) ;
  • Kim, Joon-Youn (Department of Preventive Medicine and The Industirial Medicine Research Institute College of Medicine, Dong-A University) ;
  • Chang, Hyung-Shim (Department of Pediatrics, College of Medicine, Dong-A University) ;
  • Lee, Young-Ho (Department of Pediatrics, College of Medicine, Dong-A University) ;
  • Choi, Ahn-Hong (Department of Pediatrics, College of Medicine, Dong-A University)
  • 발행 : 1992.09.01

초록

1991년 5월 1일부터 약 6개월 동안 남자 1,193명 및 여자 658명을 대상으로 우리나라 도시 거주자들의 혈중 혈색소치, ZPP치 및 연농도를 성별, 연령별로 측정한 결과 아래와 같은 결과를 얻었다. 1. 혈색소의 평균치는 남자 $14.55{\pm}1.82g/dl$, 여자 $12.61{\pm}1.18g/dl$이었으며. 20세 이상군에서는 남자가 여자보다 유의하게 높았다(p<0.05). 2. 혈중 ZPP치는 $32.54{\pm}9.88(32.09{\sim}32.99{\mu}g/dl,\;95%\;C.I.){\mu}g/dl$ 이었으며 7세 미만 소아의 혈중 ZPP치는 남아 및 여아가 $37.49{\pm}13.31{\mu}g/dl$$35.77{\pm}11.85{\mu}g/dl$로 7세 이상군의 남자 및 여자의 $31.91{\pm}8.23{\mu}g/dl$$30.11{\pm}9.11{\mu}g/dl$보다 유의하게 높았다(p< 0.05). 3. 혈중 연농도는 $23.84{\pm}4.58(23.55{\sim}24.14{\mu}g/dl,\;95%\;C.I.){\mu}g/dl$ 이었으며, 7세 미만 소아의 혈중 연농도는 남아 및 여아가 $25.10{\pm}5.21{\mu}g/dl$$24.45{\pm}4.18{\mu}g/dl$로 7세 이상군의 남자 및 여자의 $24.28{\pm}3.00{\mu}g/dl$$21.99{\pm}5.05{\mu}g/dl$보다 유의하게 높았다(p<0.05). 이상의 결과를 요약하면 우리나라 도시 거주인은 남녀 모두 전연령에 걸쳐 높은 혈중 ZPP치 및 연농도를 나타내었으며 이러한 현상은 학동기전 소아에서 더욱 현저하므로 이들에 대한 관리대책 수립이 필요하다고 사료된다.

Hemoglobin (Hb), zinc protoporphyrin(ZPP) and blood lead (PbB) levels were determined for 1,851 blood samples collected from healthy urban population to establish reliable baselines for Hb, ZPP and PbB levels by age and sex. ZPP values were analyzed with a hematofluorometer and PbB determinations were concurrently carried out using flameless atomic absorption spectrophotometry. The blood sampling period was about 6 months from May, 1991 and the summarized results were as follows ; 1. The mean value of Hb in male and female were $14.55{\pm}1.81g/dl$ and $12.61{\pm}1.18g/dl$ respectively and there was statistically significant difference(p<0.05). 2. The mean value of ZPP in pre-schoolchildren was $37.49{\pm}13.31{\mu}g/dl$ for male, $35.77{\pm}11.85{\mu}g/dl$ for female and that of ZPP in after 7 years groups was $31.91{\pm}8.23{\mu}g/dl$ for male, $30.11{\pm}9.11{\mu}g/dl$ for female and there was statistically significant difference(p<0.05). 3. The mean value of PbB in pre-schoolchildren was $25.10{\pm}5.21{\mu}g/dl$ for male, $24.45{\pm}4.18{\mu}g/dl$ for female and that of PbB in after 7 years groups was $24.28{\pm}3.00{\mu}g/dl$ for male, $21.99{\pm}5.05{\mu}g/dl$ for female and there was statistically significant difference(p<0.05).

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