The Clinical Observations in Childhood Asthma

기관지 천식의 초기 발병시 임상적 양상에 관한 관찰

A clinical analysis was done on 134 cases with bronchial asthma who were admitted to the Department of Pediatrics Yeungnam University from May 1987 to October 1991. The results were as followings; 1) The peak age of bronchial asthma was under 2 years. The sex ratio of male to female was 2.9 : 1. 2) The out-break of bronchial asthma was most common in fall, especially in September. 3) The past history of other allergic diseases were present in 22.4% of patients(30/134 cases), and the previous bronchiolitis in infancy were experienced in 12.7% of patients(17/134 cases). 4) According to the skin test for allergens done by RAST, the most common allergens were Mites and House dust. 5) Eosinophilia(T.E.C>250/min) was found in 29.1% of patients, and elevated IgE level(>200 $IU/m{\ell}$) was found in 63.2% of patients. 6) No significant differences in the serum IgE level were found between male and female patients. No significant differences in the serum IgE level were found between asthma patients with and without other allergic diseases. 7) The serum IgE level of school aged patients was significant higher than that of preschool aged(p<0.01).

1) 천식의 초기 발병 호발 연령은 5세 미만이었고 남아에서 여아보다 2.9배가 더 많았다. 2) 천식의 계절별 발생 빈도는 가을철에 많았고 특히 9월에 가장 많이 발생하였다. 3) 과거력상 다른 알레르기성 질환을 경험한 경우는 환아의 22.4%였고, 영유아시 모세기관지염을 앓은 환아는 12.7%였다. 4) RAST 검사중 가장 많은 양성을 보인 것은 진드기와 집먼지 순이었다. 5) 천식 환아에서 호산구 증다증을 보인 경우는 29.1%였고, 혈청 IgE 치가 200 $IU/m{\ell}$ 이상으로 증가된 경우는 63.2%였다. 6) 천식 환아에서 남녀간의 구분에 따른 혈청 IgE 치의 차이나 다른 알레르기성 질환의 동반 유무에 따른 혈청 IgE 치의 차이는 없었다. 7) 천식 환아에서 연령별로 조사한 혈청 IgE 치는 학동기 연령군($1139.9{\pm}470.2IU/m{\ell}$)이 학동기 전 연령군($361.6{\pm}470.2IU/m{\ell}$)에 비해 높은 수치를 보였다(p<0.01).