Applied Microscopy
- 제22권1호
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- Pages.113-127
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- 1992
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- 2287-5123(pISSN)
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- 2287-4445(eISSN)
외적요인으로서의 Chlorambucil 투여가 흰쥐 심근 노화에 미치는 영향 II. 세포화학 및 생화학적 연구
Effect of Chlorambucil as Extrinsic Factor on Aging Process of Rat Heart II. Cytochemical and Biochemical Study
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Park, Won-Hark
(Dept. of Biol., Yeungnam Univ.) ;
- Chung, Hyeung-Jae (Taegu Health Jr. Collage)
- 발행 : 1992.05.01
초록
The present study was investigated to elucidate the effects of chlorambucil the heart tissue of various-aged rats. The male rats ranging from 3 to 36 months were used. The cytochemical and biochemical changes in myocardium of the rats were studied in the aspect of free radical roles in aging process. With the goals of evaluating the potential roles of free radicals in aging process, evidence was shought for alterations of myocardial lipid peroxide levels in control and chlorambucil treated rats. The result are summarized as follows: 1. Cytochemical studies showed that the activities of
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