Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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A Simple Synthesis of 3-Substituted 1-Amino-2-thioxo-4-imidazolidinones, Isolation of the Intermediates, N-Amino-N-ethoxycarbonylmethyl-N'-aralkyl-thioureas

  • Published : 1992.10.20
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Abstract

1-Aminothiohydantoin derivatives were prepared in good yields by the reaction of alkyl or arylisothiocyanates with ethyl hydrazinoacetate hydrochloride in presence of triethylamine. The intermediates, N-amino-N-ethoxycarbonylmethyl-N'-aralkylthioure as, which were formed during the reaction and could be transformed into the appropriate 1-aminothiohydantoins, were isolated and characterized.

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References

  1. Chem. Ber. v.31 W. Traube;E. Hoffa
  2. J. Pharm. Soc. Japan v.74 H. Uota;A. Takai;T. Tanizaki;T. Yokoi
  3. J. Pharm. Phamacol. v.11 D. Jack
  4. Synthesis v.7 N. Jacobsen;J. Toelberg
  5. Bull. Nagoya City Univ. Pham. School v.4 H. Shirai;T. Yashiro;T. Hayazaki

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  1. ChemInform Abstract: A Simple Synthesis of 3-Substituted 1-Amino-2-thioxo-4- imidazolidinones, Isolation of the Intermediates, N-Amino-N- ethoxycarbonylmethyl-N′-aralkyl-thioureas. vol.24, pp.16, 1992, https://doi.org/10.1002/chin.199316183
  2. A New And Convenient Synthesis Of Some Substituted Thiohydantoins vol.29, pp.11, 1999, https://doi.org/10.1080/00397919908086188
  3. Synthesis of 3-Aminohydantoiny;-1,2-benzothiazine Derivatives vol.23, pp.12, 2002, https://doi.org/10.5012/bkcs.2002.23.12.1836