Bulletin of the Korean Chemical Society

  • 제13권2호
  • /
  • Pages.119-122
  • /
  • 1992
  • /
  • 0253-2964(pISSN)
  • /
  • 1229-5949(eISSN)
대한화학회 (Korean Chemical Society)
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An Approach to Isolation of Thromboxane Synthase (TX-SYN) by Ligand Tethered Affinity Techniques

  • Andersen Niels H. (Department of Chemistry, University of Washington) ;
  • Rhee Jaekeol (Dong-A Pharmaceutical Company Lab.)
  • 발행 : 1992.04.20
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초록

The affinity chromatographic technique was applied to the isolation of Thromboxane Synthase, with a variety of imidazolyl alkanoic acids coupled Sepharose 2B including a gel (G in Table 4) which has one free COOH group in the bound affinity ligand. The effect of ligand structure on the "affinity" and "selectivity" for thromboxane synthase isolation is described.

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참고문헌

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