Journal of Microbiology and Biotechnology
- Volume 2 Issue 4
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- Pages.278-283
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- 1992
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- 1017-7825(pISSN)
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- 1738-8872(eISSN)
Biocatalytic Production of Aldehyde by a Methanol Utilizing Yeast, Hansenula nonfermentans KYP-l Grown in Methanol-limited Continuous Culture
- Yoon, Byung-Dae (Microbial Technology Laboratory, Genetic Engineering Research Institute) ;
- Kim, Hee-Sik (Microbial Technology Laboratory, Genetic Engineering Research Institute) ;
- Kwon, Tae-Jong (Dept. of Microbial Engineering, Kon-kuk University) ;
- Yang, Ji-Won (Dept. of Chemical Engineering, Bioprocess Engineering Research Center, KAIST) ;
- Kwon, Gi-Seok (Microbial Technology Laboratory, Genetic Engineering Research Institute) ;
- Lee, Hyun-Sun (Microbial Technology Laboratory, Genetic Engineering Research Institute) ;
- Ahn, Jong-Seog (Microbial Technology Laboratory, Genetic Engineering Research Institute) ;
- Mheen, Tae-Ick (Microbial Technology Laboratory, Genetic Engineering Research Institute)
- Published : 1992.12.01
Abstract
Aldehyde production by cells of a methanol utilizing yeast, Hansenula nonfermentans KYP-1 was improved when they were grown in a methanol-limited continuous culture, in comparison with cells grown in a batch culture. A higher cell yield was also obtained in continuous culture than in batch culture. This could be due to the fact that a lower methanol concentration was maintained in the jar fermentor to minimize growth inhibition by methanol. A maximum cell productivity of 0.219 g.