한국환경보건학회지 (Journal of Environmental Health Sciences)
- 제18권2호
- /
- Pages.117-124
- /
- 1992
- /
- 1738-4087(pISSN)
- /
- 2233-8616(eISSN)
Bleomycin, Mitomycin C 및 Cadmium에 의한 CHO 세포의 적응반응
Adaptive Response in CHO Cells by Bleomycin, Mitomycin C and Cadmium
초록
Pretreatment with low concentration of Bleomycin and Cadmium rendered Chinese Hamster Ovary Cells more resistant to the induction of chromosome aberration by subsequent high concentration of same agent, however Mitomycin C did not function in that way. The cells pre-exposed to low dose of Cadmitim did not show cross-resistance to challenge dose of Mitomycin C for the induction of chromosome aberration, but cells pre-exposed to Bleomycin showed cross resistance. And the cells pre-exposed to low dose of Mitomycin C showed cross resistance to challenge of Bleomycin, but Cadmium did not.
키워드