Toxicological Research
- Volume 8 Issue 1
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- Pages.139-143
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- 1992
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
ANTIGENICITY TEST OF COPTIS RHIZOME AND CROTON TIGLIUM L. EXTRACTS(CP-2) IN GUINEA PIG AND RABBITS
-
Kang, Kyung-Sun
(College of Veterinary Medicine Seoul National University)
;
- Cho, Jae-Jin (College of Veterinary Medicine Seoul National University) ;
- Kim, Hyung-Ook (College of Veterinary Medicine Seoul National University) ;
-
Lee, Yong-Soon
(College of Veterinary Medicine Seoul National University)
;
-
Lim, Yoon-Kyu
(College of Agriculture Cheju National University)
- Published : 1992.06.01
Abstract
Antigenicity tests-ASA(Active Systemic Anaphylaxis), PSA(Passive Systemic Anaphylaxis), PCA(Passive Cutaneous Anaphylaxis)-of CP-2(Green cross Co). were performed according to the established regulations of National Institute of Safety Research. The results were as follows. 1. No specic clinical signs related anaphylaxis were observed, therefore, it was considered that CP-2 had not antigenicity in guinea pigs and rabbits. 2. No blue spots were observed on the back of guinea pig in the PCA test` CP-2 related IgE was not produced.