Archives of Pharmacal Research
- 제15권3호
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- Pages.191-195
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- 1992
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- 0253-6269(pISSN)
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- 1976-3786(eISSN)
Synthesis of 6'-Substituted Dobutamine Analogues
초록
Two 6'-substituted dobutamine analogues (1, 2) were synthesized from the coupling reaction of dopamine with the corresponding ketones. The ketone (8) was obtained from 4-nitrosalicyladehyde via 6 synthetic steps while the ketone (12) was prepared from 2-methyl-5-nitrobenzoic acid via 7 synthetic steps. Another synthetic attempts were also reported.
키워드