Journal of Oriental Neuropsychiatry (동의신경정신과학회지)

The Korean Society of Oriental Neuropsychiatry (대한한방신경정신과학회)
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The Anti-Stress and Analgesic Effects of Samhwasan

삼화산(三和散)의 항(抗)Stress 및 진통(鎭痛)에 대(對)한 실험적(實驗的) 연구(硏究)

  • 이화신 (경산대학교 한의과대학 신경정신과학교실) ;
  • 정대규 (경산대학교 한의과대학 신경정신과학교실)
  • Published : 1992.12.07
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Abstract

The present study was to carried out to investigate the anti-stress effects of Samhwasan in immobilized rats. Serum levels of catecholamine and aldosterone were measured in immobillzed rats orally receiving extracts of Samhwasan, respectively, for 1 day 7 days. And in order to investigate the analgesic effects of Samhwasan in acetic-acid injected mice, the writhing syndrome frequency was measured. The results obtained were summarized as follow ; 1. There were decreases of norepinephrine in rats receiving Samhwasan for 1 and 7 days respectively. 2. There were decreases of epinephrine in rats receiving Samhwasan for 1 day and 7 days respectively, and significant decreases were recognized in rats receiving Samhasan for 7 days. 3. There were significant decreases of aldosterone in rats receiving Samhwasan for 1 day and 7 days respectively. 4. There were significnat decreases of writhing syndrome frequency in mice receiving Samhwasan. These results appeared to suggest that Samhwasan produce the anti-stress effects and effects on pain relief.

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References

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